Purpose
The oral squamous cell carcinoma is one of the rapidly growing oral cancers and is the 6th most common cancers in the world. Squamous cell carcinoma of lower gingivo-buccal complex and tongue are most common cancers in the Indian sub-continent.
The choice of appropriate treatment for patients with oral cancer depends largely on accurate pre-treatment staging.
The value of imaging in the staging of oral cancers is in judging operability, assessment of the prognostic characteristics and dimensions of the primary tumour, depth of tumour invasion...
Methods and materials
STUDY POPULATION: INCLUSION CRITERIA:
Patients of age more than 18years of either gender who are clinically diagnosed and biopsy proven cases of oral squamous cell carcinoma and willing to undergo Pre-operative MR Imaging and definitive surgery referred from the department of Onco-surgery/Oncology were included in the study.
STUDY DESIGN & DURATION
This study was a prospective observational study with sample size of 57 and 1.5years duration after the clearance of scientific and ethical committees.
METHODOLOGY
Patients fullfilling the inclusion criteria underwent an MRI.
Imaging Techniques:...
Results
In the present study tongue was the most frequently involved site followed by buccal mucosa and the gingivo-buccal sulcus. Males were the most effected (78.95%) and the mean age was 57 years and the most commonly involved age group was 51-60 (38.6%) followed by the age group of 61-70 (33.33%). Average depth of invasion calculated on MRI was 20.4 mm and by histopathology was 20.0 mm so the depth of invasion by MRI measures 0.4mm more than the histopathological depth of invasion. Pearson’s correlation coefficient...
Conclusion
The depth of tumour invasion is directly proportional to the cervical lymph node metastasis. The statistically significant value is indicative of progressive increase in lymph node metastasis with increase in depth of tumour invasion.
Depth of invasion can be measured reliably on MRI in oral cancers which plays an important role in accurate pre-treatment staging and assessing prognosis of the patient.
Personal information and conflict of interest
M. Penuganchiprolu; NEW DELHI/IN - nothing to disclose R. Bansal; NEW DELHI/IN - Consultant at MAX SUPERSPECIALITY HOSPITAL,SAKET B. Aggarwal; New Delhi/IN - nothing to disclose U. Mukherjee; New Delhi/IN - nothing to disclose H. Chaturvedi; New Delhi/IN - nothing to disclose
References
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4963735/
https://www.ncbi.nlm.nih.gov/pubmed/19197973