Learning objectives
To review juvenile papillomatosis and its importance because of the relation with increased risk of breast cancer.
To recognize the imaging features of juvenile papillomatosis.
To share our clinical experience about juvenile papillomatosis that is not basically juvenile because it can be seen at later ages.
Background
Juvenile papillomatosis is a benign breast lesion with pathologic findings consist of papillomatosis and extensive cyst formation [1,2,3] (Fig. 1). It is first described by Rosen PP et al. in 1980 [3]. Patients have complained of a firm, well-defined, mobile mass in the periphery of the breast without nipple discharge, so clinical findings are very similar to a fibroadenoma [1,4]. It is usually solitary, but occasionally it can be seen synchronous, metachronous, and bilateral [5].
Juvenile papillomatosis is not a well known clinicopathologic entity and...
Findings and procedure details
IMAGING FEATURES:
Mammography
Mammography findings are nonspecific and usually negative. On the other hand, we can occasionally see microcalcifications and asymmetric density in mammography [1,3] (Fig. 2).
Ultrasonography
Ultrasonographic findings of juvenile papillomatosis are characteristic, but they are nonspecific due to these findings also seen other mastopathic and fibrous conditions of the breast. At ultrasonography, juvenile papillomatosis appears as ill-defined, hypoechoic heterogeneous mass and contains multiple small cysts mainly at the borders of the lesion [1,5](Fig. 3). Cysts are smaller than 2 cm [1]. Also,...
Conclusion
Juvenile papillomatosis is not a well known clinicopathologic entity. It is an underdiagnosed entity [2]. Radiologists, pathologists, and clinicians must work together to overcome diagnostic difficulties.
Although juvenile papillomatosis is benign pathology, patients with juvenile papillomatosis have increased risk for breast cancer [1].Because of this relationship, distinguishing this clinicopathological entity from other benign breast lesions is essential.
Patients who diagnosed with juvenile papillomatosis have to have more strict and early follow-ups than the healthy population [1,2,3,4].
The name of the juvenile is a pitfall. Radiologists,...
Personal information and conflict of interest
A. A. Tan; Ankara/TR - nothing to disclose G. Durhan; Ankara/TR - nothing to disclose K. Kösemehmetoğlu; Ankara/TR - nothing to disclose M. G. Akpinar; Ankara/TR - nothing to disclose A. Üner; Ankara/TR - nothing to disclose F. Demirkazik; Ankara/TR - nothing to disclose
References
1. Chung EM, Cube R, Hall GJ, et-al. From the archives of the AFIP: breast masses in children and adolescents: radiologic-pathologic correlation. Radiographics. 29 (3): 907-931.
2. Rosen PP, Kimmel M. Juvenile papillomatosis of the breast. A follow-up study of 41 patients having biopsies before 1979. Am. J. Clin. Pathol. 1990;93: 599-603.
3. Kersschot EA, Hermans ME, Pauwels C, et-al. Juvenile papillomatosis of the breast: sonographic appearance. Radiology 1988;169 : 631-633.
4. Sabate JM, Clotet M,Torrubia S, et al. Radiologic evaluation of breast disorders related...