To shown the absolute perfusion of the brain, that is not hampered by the breakdown of the blood–brain barrier. To shown another sequences that is cost-effective and noninvasive vs perfusion; the advantage of no gadolinium use. The characterization of not only of brain tumours (neuro-oncology), but also metabolic disorder, encephalomalacia, vascular and inflammatory/infections disease. Pediatric focused studies are less common, there are just a few indexed publications.

Arterial spin labeling (ASL) is a non-invasive MRI technique to measure cerebral blood flow (CBF). 1 There are well-established methods for investigating blood flow in neurological diseases, these are: dynamic susceptibility contrast (DSC) magnetic resonance imaging (MRI), computed tomography (CT), perfusion imaging, single-photon emission tomography (SPECT), and H2O15 positron- emission tomography (PET); ASL MRI has emerged as a versatile complement that warrants regular consideration in the clinical setting.1,2 In general, adults or pediatrics, the main areas of interest are cerebrovascular disease, and neuro-oncology. In cerebrovascular...

We researched our data base for the cases where the ASL sequence was performed. Then, we assessed the images and compared findings with the other sequences: FLAIR, DWI and T1 + gadolinium vs ASL; a discussions was made about it. We took examples of differents pathologies, where were included: brain tumors, metabolic disorder, encephalomalacia, vascular and inflammatory/infections disease. All patients were scanned on a clinical 3T MR imaging scanner. At the beginning the idea was to include patients with brain tumours, because it is the...

Cerebral blood flow assessed by ASL has no significance on its own, it has to be included among the other sequences performed, including gadolinium dependent methods. ASL can be use not only for brain tumors but can be applied to metabolic disorder, encephalomalacia, vascular and inflammatory/infections disease. The goal is promote the use and knowledge of ASL for children for an application in a wider range of pathologies.

Contact details: Dr. Vanessa Estefania Montaño Claure Resident in training. Department of Radiology, Hospital Regional de Alta Especialidad de Oaxaca. Email: [email protected] Dr. Eduardo Miguel Flores Armas Neuro Radiology Section. Department of Radiology, Hospital Infantil de México, Federico Gómez, Calle Dr. Márquez 162, Doctores, 06720 Ciudad de México, CDMX Email: [email protected] V. E. Montaño Claure; Ciudad de Mexico/MX - nothing to disclose E. M. Flores Armas; Ciudad de Mexico/MX - nothing to disclose

Grade M, Hernandez Tamames JA, Pizzini FB, Achten E, Golay X, Smits M. A neuroradiologist's guide to arterial spin labeling MRI in clinical practice. Neuroradiology 2015; 57(12):1181-202. Ferré JC, Bannier E, Raoult H, Mineur G, Carsin-Nicol B, Gauvrit JY. Arterial spin labeling (ASL) perfusion: techniques and clinical use. Diagn Interv Imaging 2013; 94(12):1211-23. Wang J, Licht DJ, Jahng G-H et al Pediatric perfusion imaging using pulsed arterial spin labeling. J Magn Reson Imaging 2003; 18(4):404–413. Petcharunpaisan S, Ramalho J, Castillo M. Arterial spin labeling in...