Gadoxetate disodium is an MRI paramagnetic contrast agent that allows a dynamic liver study like a “traditional” contrast medium, while at the same time enabling the study of hepatobiliary phase and providing information on hepatocyte uptake. Due to reduced dose of administration compared to a traditional contrast medium (0.1 ml/kg vs 0.2 ml/kg), and to reduced content of gadolinium (0.025 mmol/ml vs 0.1 mmol/ml) [1], amplitude and duration of enhancement peak can be reduced, making it difficult to synchronize the acquisition and the passage of...

We observed MR liver exams with Gd-EOB-DTPA acquired with a 1.5T scanner (gradients 45 mT/m, slew rate 200 mT/m/ms) of 146 patients, 84 with sequential K-Space and 62 with centric K-Space. The study was retrospective for “sequential patients” and perspective for “centric patients”. We used a 3D Rapid acquisition GRE FID imaging sequence (Figure 1)(Figure 2), acquired with a 18 channels Body coil in combination with a 32 channels Spine coil. For sequential K-Space filling and an acquisition time of 21 seconds, the time to...

With sequential K-Space, 50% of the patients showed artifact in arterial phase. Of these, 95% were acquired with matrix 320 and 5% with matrix 256. In 70% of cases the arterial phase was early (delay for scan was fixed at 35 seconds). With centric K-Space, only 14% of patients showed artifact in arterial phase. 66% were acquired with matrix 320, 34% with matrix 256 (Figure 5).

With centric K-Space we observed that artifact slacks off to 14% (p

1-Alice Pratesi, Radiographer,[email protected], Santa Maria alle Scotte University Hospital, Siena, Italy - nothing to disclose 2- Simona Covizzoli, Radiographer,[email protected], Careggi University Hospital, AITIRM, Florence, Italy - Founder at AITIRM 3- Stefano Chiti, Radiographer,[email protected], Careggi University Hospital, AITIRM, Florence, Italy - Founder at AITIRM 4- Daniele Ermini, Radiographer,[email protected], Careggi University Hospital, Florence, Italy - Nothing to disclose

[1] AIFA - Agenzia Italiana del Farmaco (2018) [2] Huh J. et al., Troubleshooting Arterial-Phase MRI of Gadoxetate Disodium-Enhanced Liver, Korean Journal of Radiology, 16(6): 1207–1215 (2015) [3] Haradome H. et al., Can MR fluoroscopic triggering technique and slow rate injection provide appropriate arterial phase images with reducing artifacts on Gadoxetic acid–DTPA (Gd-EOB-DTPA) - enhanced Hepatic MR imaging?, Journal of Magnetic Resonance Imaging 32:334–340 (2010) [4] Zhang H. et al., 3D Contrast-Enhanced MR Angiography, Journal of Magnetic Resonance Imaging 25:13–25 (2007) [5] Deshmane A. et...