Learning objectives
To determine preoperative computed tomography (CT) features that represent an absolute contraindication for lung transplant.
Highlight CT features that could affect therapeutic decision, change surgical approaches or predict worst outcomes.
Background
The first lung transplantation with long-term survival was achieved in 1983, at the University of Toronto. Sincethen, lung transplantation has become an accepted treatment option for patients with various forms of progressive lung diseases that do not respond to non-transplant therapies. Various studies extensively addressed peri- and postoperative complications after lung transplantation, however preoperative imaging considerations have been scarcely documented. In lung recipients, imaging is essential to assess the suitability of the transplant candidate, to look for clinically occult malignancy, to match donor and recipient...
Findings and procedure details
Introduction:
The most common indications for lung transplantation are described in [Fig. 2].
Pre-operative imaging examinations are important components of strenuous work-up studies in lung transplant candidates. Imaging protocol in our radiology department consists of chest radiography and enhanced chest CT.
Important data to record in chest CT of the transplant recipient
1. Parenchymal disease:
1.1Underlying pulmonary disease:
Although quantitative ventilation-perfusion scanning is the mainstay for selecting which lung will be transplanted for single-lung transplant procedures, chest CT can change the selected lung by depicting...
Conclusion
Lung transplantation has increased worldwide with steadily improving outcomes. Besides notorious advancements in surgical and anesthetic techniques, a multidisciplinary approach optimizing recipient selection and management, which includes preoperative lung CT imaging, has contributed to that outcome.
Radiologists must be knowledgeable in identifying clinical conditions associated with poor outcomes and anatomic abnormalities with implications for surgical techniques in lung transplantation.
Personal information and conflict of interest
V. Carvalho; Lisbon/PT - Author at CHULC J. M. Almeida; Lisbon/PT - nothing to discloseJ. E. Reis; Lisbon/PT - nothing to discloseC. A. S. Ruano; Lisbon/PT - nothing to disclose A. Araujo; Lisbon/PT - nothing to disclose
References
1.Weill, D et al., A consensus document for the selection of lung transplant candidates: 2014 — An update from the Pulmonary Transplantation Council of the International Society for Heart and Lung Transplantation; J Heart Lung Transplant (2015); 34:1–15.
2.Backhus, L et al., Imaging in Lung Transplantation Surgical Considerations of Donor and Recipient, Radiol Clin N Am (2015).
3.Belli, EV et al., Lung cancer following lung transplant: single institution 10 year experience. Lung Cancer (2013); 81(3):451–4.
4.Shigemura N et al., Lung transplantation in patients with prior...