Review the main systemic diseases that can determinate involvement of the mammary structures; Discuss the most common findings of these conditions on breast imaging modalities; Acquaint the general radiologists with these findings and encourage them to always include these disorders in their range of diagnostic possibilities; Exemplify these findings with illustrative cases from our institution;

Even though most of breast imaging exams focus on detecting cancer, there are some systemic conditions that can express themselves with breast commitment, and can provide an important diagnostic challenge, especially if clinical information is not available. Although uncommon, they can be included in the differential diagnosis of the main radiological findings in all breast imaging modalities, including masses, calcifications, skin changes, lymphadenopathy and asymmetries.

This educational exhibit reviewed selected cases from our picture archiving and communication system (PACS), which we illustrate with mammography, ultrasound and magnetic resonance imaging. We highlight verified examples of the above-mentioned conditions, mentioning their characteristics on breast imaging modalities. 1. Cardiovascular disease a) Congestive heart failure Imaging findings At mammography, arterial and arteriolopathy are expressed by calcifications following the shadow of the vessel. The second characteristic presents itself as skin thickening, with increased density of the fibroglandular tissue and, sometimes, engorgement of veins Fig. 1...

There is no doubt that thinking about systemic while reading a breast exam requires not only attention but basic knowledge about the subject. As general radiologists are not always in contact with these kind of findings, the importance of the present theme is justified. With these information solidified, the radiologist can increase his radiological repertoire and avoid pitfalls and unnecessary interventions.

P. H. G. D. Andrade; São Paulo/BR - nothing to disclose E. Endo; São Paulo/BR - nothing to disclose R. S. Omori; São Paulo/BR - nothing to disclose P. H. H. Souza; São Paulo, SÃO PAULO/BR - nothing to disclose C. S. Franco; São Paulo/BR - nothing to disclose L. A. Silva; Sao Paulo/BR - nothing to disclose

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