To investigate the imaging features and clinical value of post lymphangiographic CT (PLCT) after direct lymphangiography in diagnosis and differential diagnosis in protein-losing enteropathy (PLE).
Methods and materials
Fifty-seven patients diagnosed as PLE were recruited in this retrospective study from Jan of 2011 to June of 2017, including 42 primary intestinal lymphangiectasia (PIL), and 15 other kinds of PLE. All patients underwent PLCT after direct lymphangiography, endoscopy and pathological examinations. All the imaging data were blinded reviewed by two experienced radiologists respectively. Image analysis of PLCT were as following: (1) intestinal wall thickening, (2) edematous lesions, including mesentery fat obscure, ascites, pleural and pericardial effusions, (3) abnormal distribution of contrast media in intestinal...
Compared with other kinds of PLE, patients with PIL demonstrated lower onset age （14.7 ± 10.6 Vs. 38.8 ± 10.7，P＜0.01）. For imaging features, (1) intestinal wall thickening (64.2% Vs. 40.0%), (2) edematous lesions, including ascites (23.8% Vs. 26.7%), pleural and pericardial effusions (28.6% Vs. 46.7%), (3) abnormal distribution of contrast media in intestinal wall and mesentery (54.8% Vs. 6.7%), indicating intestinal lymphangiectasia, (4) lymph fluid reflux in lymphatic circulation, indirect imaging feature that abnormal contrast media distributed on the opposite side of cannulated foot in...
PLCT after direct lymphangiography demonstrates capability in detection of location, distribution and range of abnormal lymphatics, which is useful for differential diagnosis and therapeutic adoptions for PLE.
Personal information and conflict of interest
J. Dong; Beijing/CN - nothing to disclose R. Wang; Beijing/CN - nothing to disclose
1. Dong J, Xin J, Shen W, et al. CT Lymphangiography (CTL) in Primary Intestinal Lymphangiectasia (PIL): A Comparative Study with Intraoperative Enteroscopy (IOE)[J]. Acad Radiol. 2019;26(2):275-281.