Prostate cancer is known as second most frequent malignancy in men worldwide, causing 358,989 deathsin 2018 [1, 2] Although transrectal ultrasound-guided (TRUS) systematic biopsy of prostate issued for detecting prostate cancer in the suspected patients [3-7] but a considerable false negative results has been reported in the first time biopsy [8]. In such circumstances, usually second biopsy and sometimes if the second one is negative, third biopsy is recommended [8-10].Some limitations of repeating TRUS-guided systematic biopsy of prostate leads to develop more reliable method; Multiparametric...

In total number of 84 patients who were suspicious for prostate cancer due to elevated PSA and with history of negative previous TRUS guided systematic biopsy of prostate and were referred for repeating biopsy to our radiology department ,Multiparametric MRI of prostate performed to detect any suspicious lesion for prostate cancer.MRI was performed in all patients by a 1.5 tesla MR machine (Avento,Siemens,Erlangen, Germany) 18 channels by using endorectal and pelvic phased array coils. We used combination of four parameters including signal changes in T2...

Totally 1176 biopsies in TRUS systematic method (14 biopsies in each patient). Mean age of patients was 65.7±8.6 years (50-84). The mean PSA of all patients was 7.3±2.7 (3.2-15). All patients showed negative isotope bone scan. Neither of patients had lymphadenopathy or pelvic skeletal metastasis. Mean age of patients with positive biopsy for cancer was 64.4±8.3 and in patients without cancer was 66.3±8.7 (P-value=0.37). The mean PSA of patients with positive biopsy for prostate cancer was 8.1±2.7 while it was 7±2.6 in patients without positive...

In comparison between systematic and targeted biopsy, we found that the systematic biopsy can detect less cancers with obtaining huge number of biopsies but targeted biopsy can detect more cancers with little number of biopsies. Then targeted biopsy is more accurate and with higher cancer detection rate. On the other hand reduction in number of biopsies,reduce complications. We conclude that Multiparametric MRI of prostate using endorectal coil is a valuable modality for detection of prostate cancer and we recommend to be used before re-biopsy for...

Mohammadreza Khaleghi; Tehran/IR M.D. – M.P.H, Radiology Resident, Department of Radiology, Iran University of Medical Sciences, Tehran, Iran E. Mail: [email protected] Mahyar Ghafoori; Tehran/IR M.D., Associate Professor of Radiology, Department of Radiology, Iran University of Medical Sciences, Tehran, Iran E- Mail: [email protected] Paria Arman; Tehran/IR M.D, Tehran University of Medical Science, Tehran, Iran E- Mail: [email protected] Authors have nothing to disclose.

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