Retrospective, Cancer, Biopsy, Ultrasound, Mammography, Breast, Observational, Performed at one institution
M. A. Leão, L. Veras, A. watanabe, N. Menezes; Barretos/BR
Adenoid cystic carcinoma (ACC) of the breast is a rare histological subtype (1). It occurs in less than 0.1% of patients with breast cancer (2). The phenotype is typically a triple negative carcinoma (negative for estrogen and progesterone receptors and negative receptor for human epidermal growth factor (HER-2)) (3).
Imaging features of ACC of the breast are usually nonspecific and vary widely (4). On mammography, it has been described as asymmetric densities or irregular masses. On ultrasound imaging, ACC often presents as an irregular, hypoechoic solid or heterogeneous mass with vascularity on power Doppler (5). There are only a few reports evaluating the magnetic resonance imaging (MRI) characteristics of ACC of the breast (2). The tumor has a benign-appearing, circumscribed mass and shows a moderately hyperintense signal on T2-weighted (6) with rapid enhancement (but no washout) on T1 weighted (7). Patients with ACC are usually symptomatic and most commonly present with a palpable mass. Other possible symptoms include breast pain and nipple retraction (8-9).
In this study, we aimed to describe the imaging findings and the clinical, pathological and immunohistochemical features of these tumors based on a review of 13 cases in our hospital.