Retrospective, Cancer, Biopsy, Ultrasound, Mammography, Breast, Observational, Performed at one institution
M. A. Leão, L. Veras, A. watanabe, N. Menezes; Barretos/BR
Upon review of our cancer registry database, we found 13 patients who had received a diagnosis of ACC. The mean patient age was 63.8 years (52-87 years). All cases were HER-2 negative. There was one case in which estrogen and progesterone receptors were positive (Figure 1). The tumor size ranged from 2.0 to 7.5 cm. Six patients underwent mastectomy with sentinel lymph node biopsy, representing 46% of patients. The nodal status was positive in just one case (Table 1). Three patients reported a familial history of breast cancer. There was only one male patient (figure 2).
The symptoms reported by patients included palpable masses and breast pain. The most common symptom was a palpable mass (53,8%). Left breast was the most often affected (61,5 %). Image findings on mammography included masses, calcifications, architectural distortion and nipple retraction. The most common image finding on mammography was a mass (Figure 3). Calcifications were encountered in two cases (figure 4) and architectural distortion was reported in only one case. The majority of patients (53,8%) had follow-up, and 85,7 % of these patients were free of disease on last follow-up (Table 2). There was only one case of local recurrence and one case of distant metastasis to the lung after treatment. In our series, one patient presented with a simultaneous malignancy in the contralateral breast (intraductal carcinoma) with an imaging finding of architectural distortion that had only been identified by tomosynthesis (figure 5). Our study had some limitations. Due to its retrospective nature, some of the patient data and imaging were not could be obtained.