Fatty liver disease is a widespread pathology [1]. It is found to be associated with conditions such as non-alcoholic fatty liver disease (NAFLD), viral hepatitis, and alcoholic liver disease. The progression of these diseases can lead to liver cirrhosis and hepatocellular cancer. Timely detection of hepatic steatosis can prevent disease progression and avoid liver transplantation. The most accurate methods to diagnose liver steatosis are biopsy and MRI, which correlate with each other [2, 3]. Among the methods for the identification of hepatic steatosis are non-contrast...

Study design: We performed the study retrospectively. Patients: We analyzed 30000 patient records from 2017 to 2019. LDCT was done within the framework of the Moscow Lung Cancer Screening trial or per the preventive examination of medical institutions employees. The routine CT scan of these patients was carried out as a follow-up examination. Inclusion criteria: We included patients with both thoracic non-contrast CT and an LDCT and the time interval between the studies of less than 27 days. Exclusion criteria: The absence of CT-LDCT pair,...

Patients: 76 patients with CT-LDCT pairs were selected for the study. Of these, 15 were excluded from the study due to incorrect segmentation in image processing (Figure 2, 3). Thus, we used data from 61 patients for statistical analysis (Figure 4, 5), which is two patients less than the initially required number. However, this lack of subjects is not critical for obtaining reliable data. Patient age was from 21 to 83 years old. The average age was 53 years. The ratio of men to women...

The result of the statistical analysis allows us to conclude that from LDCT-based liver density measurement, it is possible to draw preliminary conclusions about the state of liver parenchyma. An analysis of the image noise/liver density ratio on the LDCT shows an inversely proportional relationship: the higher the noise level, the more significant a “decrease” in liver density. Also, we compared liver density as measured by routine CT and LDCT in subgroups divided by initial densities. No significant differences were found in all but 40-50...

A. P. Gonchar; Moscow/RU - Author at State Budget-Funded Health Care Institution of the City of Moscow - Speaker at State Budget-Funded Health Care Institution of the City of Moscow "Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Moscow Health Care Department" - Investigator at State Budget-Funded Health Care Institution of the City of Moscow "Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of Moscow Health Care Department" A. Elizarov; Moscow/RU - Investigator at State Budget-Funded Health Care Institution of...

G. Bedogni, L. Miglioli, F. Masutti, C. Tiribelli, G. Marchesini, S. Bellentani Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology, 42 (1) (2005), pp. 44-52 Rajarshi Banerjee, Michael Pavlides, Elizabeth M. Tunnicliffe, Stefan K. Piechnik, Nikita Sarania, Rachel Philips, Jane D. Collier, Jonathan C. Booth, Jurgen E. Schneider, Lai Mun Wang, David W. Delaney, Ken A. Fleming, Matthew D. Robson, Eleanor Barnes, Stefan Neubauer. Multiparametric magnetic resonance for the non-invasive diagnosis of liver disease. J Hepatol....