Keywords:
Computer applications, MR physics, Paediatric, CT, Image manipulation / Reconstruction, MR, Computer Applications-3D, Radiation safety, Dosimetric comparison, Image verification
Authors:
M. Alhilani1, H. Jeong2, G. Ntolkeras2, S. R. Atefi2, L. Zöllei2, A. Pourvaziri2, M. H. Lev2, E. P. Grant2, G. Bonmassar2; 1London/GB, 2Boston, MA/US
DOI:
10.26044/ecr2021/C-10139
Purpose
Human body modelling and simulation have been widely used in industry, academia, and government for medical devices efficacy and safety testing in various areas, including optics, electromagnetics, mechanics, ultrasound, etc. Even though Magnetic Resonance Imaging (MRI) is generally considered safe, clinical MRI studies are increasing, and new safety challenges appear, such as paediatric MRI in patients with implants. Every existing whole-body and partial voxel model included between 10 and 78 tissue compartments and were modeled with different ages ranging from newborns to 84-year-old. However, every current paediatric model either lacks any detailed brain segmentation, or was morphed from an older model with resulting anatomical inaccuracies that may compromise the simulation accuracies. Several studies have been conducted to develop paediatric models, many of them have gaps in the validation of their segmentation anatomical quality or low resolution.1-5 In order to address these limitations, we introduce MARTIN, a 29-month-old boy whole-body model, which includes 28 brain and 86 body tissue compartments. MARTIN is a native numerical model, it was segmented directly from MRI and CT images of a 29-month-old child, and no morphing was performed.