The mean age of the patients was 54.2 years. The most common histological subtype was infiltrating ductal carcinoma (92 cases, 90.29%) followed by infiltrating lobular carcinoma (6 cases, 5.83%), mucinous carcinoma (3 cases, 2.91%) and solid intraductal carcinoma (1 case, 0.97%).
Regarding molecular subtypes, the most common was luminal B HER2- (39 cases, 37.86%) followed by triple negative (TN) (24 cases, 23.33%), luminal B HER2 + (17 cases, 16.50%), HER2 (2 cases, 11.65%) and Luminal A (11 cases, 10.68%) (Fig. 9)
Radiological response (Fig.10A):
- Complete radiological response: 44.66% (46 cases)
- Major partial response: 33.01% (34 cases)
- Minor partial response 16.50% (17 cases)
- No response: 5,82% (6 cases)
Pathologic response according to Miller and Payne grading system (Fig. 10B):
- Grade 1: 7.77% (8 cases)
- Grade 2: 7.77% (8 cases)
- Grade 3: 28,16% (29 cases)
- Grade 4: 22.33% (23 cases)
- Grade 5: 33.98% (35 cases)
Correlation between radiological response and pathologic response was 53.39%, with underestimation in 9.70% and overestimation in 36.89%.
The highest percentage of correlation was obtained in HER2 (66.66%) followed by luminal B HER2 + (64.7%) and triple negative (62.5%) molecular subtypes (Fig. 11)
The highest proportion of false positives and negatives was obtained in luminal A subtype (72.72%) and HER2 subtype (16,66%), respectively.