Multiparametric Brain MRI Evaluation in Patients with Cognitive Impairment

Congress:

ECR 2022

Poster Number:

C-10232

Type:

Scientific Exhibit

Keywords:

Neuroradiology brain, MR, MR-Diffusion/Perfusion, Computer Applications-3D, Computer Applications-Detection, diagnosis, Computer Applications-General, Dementia

Authors:

N. Zdanovskis, A. Platkajis, A. Kostiks, K. Šneidere, A. Stepens, G. Karelis

DOI:

10.26044/ecr2022/C-10232

DOI-Link:

https://dx.doi.org/10.26044/ecr2022/C-10232

References

1. Dickerson BC, Bakkour A, Salat DH, et al. The cortical signature of Alzheimer's disease: regionally specific cortical thinning relates to symptom severity in very mild to mild AD dementia and is detectable in asymptomatic amyloid-positive individuals. Cereb Cortex. 2009;19(3):497-510. doi:10.1093/cercor/bhn113

2. Busovaca E, Zimmerman ME, Meier IB, et al. Is the Alzheimer's disease cortical thickness signature a biological marker for memory?. Brain Imaging Behav. 2016;10(2):517-523. doi:10.1007/s11682-015-9413-5

3. Dale AM, Fischl B, Sereno MI. Cortical surface-based analysis. I. Segmentation and surface reconstruction. Neuroimage. 1999 Feb;9(2):179-94. doi: 10.1006/nimg.1998.0395. PMID: 9931268.

4. FreeSurfer Software, https://surfer.nmr.mgh.harvard.edu/fswiki/FreeSurferWiki

5. Nasreddine ZS, Phillips NA, Bédirian V, Charbonneau S, Whitehead V, Collin I, Cummings JL, Chertkow H. The Montreal Cognitive Assessment, MoCA: a brief screening tool for mild cognitive impairment. J Am Geriatr Soc. 2005 Apr;53(4):695-9. doi: 10.1111/j.1532-5415.2005.53221.x. Erratum in: J Am Geriatr Soc. 2019 Sep;67(9):1991. PMID: 15817019.

Fig 1: Descriptive statistics where statistically significant differences between...

Fig 2: Spider-diagram with obtained values for hippocampal volume and Alzheimer's...