The aim of the study was to describe the typical radiological features of left ventricular remodeling in patients with hypertrophic cardiomyopathy (HCM) following alcohol septal ablation.

HCM is a genetically determined disease leading to left ventricular (LV) hypertrophy. Up to 70% of patients with HCM have a varying degree of left ventricular outflow tract (LVOT) obstruction. The presence and degree of obstruction influence the symptomatic presentation, treatment strategies, and prognosis of affected individuals. Septal reduction therapy with alcohol septal ablation (ASA) is utilized to relieve symptoms refractory to maximal medical therapy [1-4]. During the ASA procedure, the operator must identify and inject a small amount of alcohol into the septal branches,...

ASA results in myocardial infarction. Accordingly, typical cardiac CT and MRI findings are fibrosis or scar tissue formation in the basal third of the interventricular septum (Fig.1), which are accompanied by substantial thinning of the treated area, relieving of LVOT obstruction and reduction of the subaortic gradient. Frequently, the first septal branch ( FSB) of the left anterior descending artery can be a small caliber(<1 mm in diameter), that supplies only a minor subaortic part of the septum, but not the part related to the...

Cardiac CT and MRI allow to assess the morpho-functional state of the LV, evaluate the reduction of thickness of interventricular septum with the presense of fibrosis caused by ASA, and enable us to measure the basal segments of LV in HCM paients more accurately than echocardiography does.

M. Tregubova: Nothing to disclose K. Rudenko: Nothing to disclose M. Tkachenko: Nothing to disclose P. Danchenko: Nothing to disclose

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