Learning objectives
- Exploring central skull base anatomy- Describing key imaging features and strategies for differentiating central skull base lesions
Background
The central skull base, marking the boundary between the intracranial and extracranial regions, can be affected by intrinsic lesions originating from the skull base or neighboring structures above and below. Because clinical assessment is limited, cross-sectional imaging has become crucial for diagnosing, planning treatment, and monitoring patients with skull base lesions.
Findings and procedure details
1- Anatomy of central skull baseKnowledge of skull base anatomy is required for correct imaging diagnosis and for accurate delineation of lesions (Figure 1).2- Pathologies of central skull base
Metastasis (Figure 2)
Origin and location: The lung, breast, prostate, and kidney are the most common primaries to metastasize to the skull base
Clinical aspect: Metastasis is the most common neoplasm affecting the skull base in an adult patient.
Imaging features: Osteolytic metastasis typically forms a destructive mass centered in the bone with no sclerotic rim...
Conclusion
Central skull base lesions may exhibit typical imaging findings in expected locations, but variations can occur. Therefore, enhancing diagnostic accuracy for skull base lesions requires understanding clinical issues and being aware of imaging feature variations. Some imaging findings and clinical information may help us to reach the correct diagnosis (Table 1 and Table 2).
Personal information and conflict of interest
F. Atak:
Nothing to disclose
Y. Yaraşir:
Nothing to disclose
A. Karaosmanoğlu:
Nothing to disclose