BAC modeling is a viable companion to traditional mammography, as it can be performed with high accuracy and within minutes of the exam.  Moreover, a quantitative BAC score can offer insight into the presence or absence of atherosclerotic calcifications within other medium and large vessels in the body.  In our model, quantitative BAC assessment predicted a higher rate of clinically significant atherosclerotic disease in large and medium vessels when BAC score was 3 or higher.  In a sense, the presence and amount of calcium within the arteries of the breast can provide a window to the amount of calcium within other arteries as the pathophysiology of the calcium deposits is identical.  A quantified BAC score can offer insight into the degree of “systemic vasculopathy” within a patient, potentially identifying those that could benefit from enhanced cardiovascular screening.