Keywords:
Connective tissue disorders, Laboratory tests, Diagnostic procedure, Contrast agent-intravenous, MR, Soft tissues / Skin, Contrast agents, Cardiac
Authors:
M. M. BARIS1, M. Birlik1, G. Kenar1, N. S. GEZER2; 1IZMIR/TR, 2İzmir/TR
Results
Myocardial LE was detected in 11 of 27 patients (Fig.2 ).
Tzelepis et al.
(5) reported in their study that in SSc,
myocardial LE was characteristically at midwall,
with a linear pattern in all of the patients and some of the patients also had additional patchy and nodular LE pattern.
In our study,
in six patients linear or strap like LE pattern (Fig.
3) and in five patients focal or nodular LE area (Fig.4) has been detected.
In our study there were some patients who has only nodular LE pattern.
But patient number in our study was limited and studies with larger series are needed.
Clinical characteristics and MRI findings of patient population were summarized in Table 1.
No statistically relation found between MRSS and LE in general group or diffuse and limited disease subgroups (p =0,716,
p=0,711,
p=0,124).
Despite of studies (6,
7) suggests that heart involvement might be more prevalent in the diffuse subtype,
no relation was detected statistically between LE and disease type (diffuse/limited) (p=0,264) in our study.
There was no relation between anti centromere antibody and LE statistically (p= 0,273).
There was an inverse relationship between scl-70 antibody positivity and LE positivity and it was statistically significant (p=0,022).
Distribution of patients according to anti scl-70 antibody and LE positivity was shown in Table 2.
Statistically there was no relation between duration of disease and LE presence.(p=0,804).
Table 1: Clinical Characteristics and MRI findings of patients population
M/F,
n
|
4/23
|
Mean age(years)
|
56
|
Limited/diffuse SSc,
n
|
11/16
|
Anticentromere antibody,
n(%)
|
4(14)
|
Anti-scl-70 antibody,
n(%)
|
15(55)
|
ANA antibody,
n(%)
|
26(96)
|
Mean disease duration since non-Raynaud's phenomenon(years)
|
10
|
Mean disease duration since Raynaud's phenomenon(years)
|
13
|
Mean MRSS
|
9
|
LE in cardiac MRI,
n(%)
|
11(40)
|
Table 2: Distribution of patients according to anti-scl-70 antibody and late enhancement positivity .
|
Anti-scl-70 antibody
|
Total
|
Negative
|
Positive
|
|
Late Enhancement
|
Negative
|
4
|
12
|
16
|
|
Positive
|
8
|
3
|
11
|
Total
|
|
12
|
15
|
27
|