Congress:
EuroSafe Imaging 2019
Keywords:
Neoplasia, Computer Applications-Detection, diagnosis, CT, Radioprotection / Radiation dose, Action 10 - EuroSafe Imaging Stars
Authors:
M. Buzoianu, R. A. Capsa, M. Grasu, I. G. Lupescu
DOI:
10.26044/esi2019/ESI-0088
Background/introduction
Multiple myeloma (MM) is the second most common hematological malignancy and is based on a cytogenetically heterogeneous proliferative disorder of clonal plasma cells.
Although it can affect different organs,
the bone skeleton is highlighted both in terms of prevalence and clinical impact.
Despite the striking advances in MM therapy,
bone disease can remarkably affect the patient’s quality of life (1).
Many imaging techniques have been proposed for the detection of MM skeletal involvement (1),
but computed tomography (CT) was the one that has been included in the updated criteria of MM (2).
The main disadvantage of CT is a considerably high radiation dose (2).
Therefore,
low-dose CT protocols could be a solution (2).
The aim of this study is to analyze the usefulness of Whole-Body Low-Dose CT (WBLDCT) in the evaluation of patients with MM and to make adjustments in the standard CT protocol (2).