Learning objectives
To review and discuss the imaging appearances of biopsy-proven cases of mesenteric fibromatosis, Rosai-Dorfman disease and inflammatory myofibroblastic tumour; with the aims of aiding radiologists in identifying these processes to assist guiding patient management.
Background
As the availability and use of diagnostic imaging continues to increase, so too does the early/incidental discovery of neoplasms and conditions which can simulate neoplasms. These entities need to be distinguished from true tumours and other benign conditions, such as infection, and are critical for radiologists and pathologists to be aware of in their differential diagnostic repertoires. This is apparent in the increasing literature available on these. Mesenteric fibromatosis, Rosai-Dorfman disease and inflammatory myofibroblastic tumour are relatively rare mimics of tumours on imaging. We review...
Imaging findings OR Procedure details
Mesenteric fibromatosis (MF) is an example of an idiopathic fibrosing disorder, a group of locally aggressive fibroproliferative conditions which can infiltrate and recur. They can occur in the mediastinum, small and large bowel and mesentery. [1]
MF can occur throughout adulthood with no race or gender predilection. Interestingly, 13% of patients with MF are found to have the Gardner variant of familial adenomatous polyposis, with previous abdominal surgery as an important risk factor for the development of MF. Bowel obstruction, fistula formation and perforation are...
Conclusion
It is becoming increasingly important for radiologists to be aware of lesions and processes mimicking tumours. We explore examples of these entities with cases of mesenteric fibromatosis, Rosai-Dorfman disease and inflammatory myofibroblastic tumour.
References
Phillips, S., Restrepo C. S. & Chintapalli, K.. Applied Radiology: The Journal of Practical Medical Imaging and Management. Mimics of neoplasia: Common lesions and findings misdiagnosed as malignancy. San Antonio, Texas: Applied Radiology; [updated 2012 February 28; cited 2021 March 3]. Available from: https://appliedradiology.com/articles/mimics-of-neoplasia-common-lesions-and-findings-misdiagnosed-as-malignancy
Mar, W. A., Yu, J. H., Knuttinen, M. G., Horowitz, J. M., David, O., Wilbur, A. & Menias, C. O.. Rosai-Dorfman Disease: Manifestations Outside of the Head and Neck. American Journal of Roentgenology. 2017 April; Volume 208(No 4): p721-732. Available from:...