Purpose
1) To assess the ability of CT angiography in evaluating degree of carotid stenosis and nature of plaque and studying mutual relationship if any.
2) To investigate the relationship between degree of stenosis and severity of CT detectable brain lesions.
3) To attempt to characterize the carotid plaque,
if any and investigate the relationship between plaque type (fatty,
mixed and calcified) and extent of brain lesions.
Methods and Materials
The study was conducted in the Department of Radiology at Guru Gobind Singh Hospital,
Jamnagar from September 2010 to August 2012.
NECT Brain and CT angiography examinations of 28 patients were performed who fulfilled below mentioned inclusion and exclusion criteria.
Images were analyzed on dedicated workstations and correlated mutually.
NECT Brain
The images were acquired with a helical 16 slice MDCT scanner (General Electric,
Brightspeed).
Acquisitions were performed without injection of contrast medium,
from the base of the skull to the vertex in the plane...
Results
CLINICAL AND EPIDEMIOLOGICAL RISK FACTOR CORRELATION
WITH CT BRAIN LESION
With CT brain lesion
(23)
Symptoms
23 (100)
Mean age (yrs)
63
Male
13 (56)
Female
10 (43)
Ischemic heart disease (IHD)
4 (17)
Tobacco use
14 (61)
Hypertension
11 (48)
Diabetes Mellitus
15 (65)
Dyslipidemia
10 (43)
ASSOCIATION WITH DEGREE OF STENOSIS
Studied
(28 patients)
Patients with >70% stenosis (minimum one vessel) (n=7)
Patients with <70% stenosis (both vessels)
(n=17)
Normal angiography
(n=4)
Chi squre
=0.201
P=0.9046
CT brain lesions (23)
6 (86)
14...
Conclusion
The findings derived from the present study can be summarized as below:
Multiple epidemiological risk factors are associated with ischemic brain lesions on CT,
with strongest association being seen with diabetes mellitus in studied population.
No significant association has been noted between symptoms and degree of stenosis.
This finding is variably supported in the previous literature.
Severe vascular stenosis (>70%) alone is shown to have NO significant association with CT brain lesions as compared to patients having <70% stenosis,
however when associated with fatty plaque...
References
M.
Eesa,
M.D.
Hill,
A.
Al-Khathaami,M.
Al-Zawahmah,
P.
Sharma,
B.K.
Menon,
S.
Tymchuk,
A.M.
Demchuk,
M.
Goyal.Role of CT Angiographic Plaque Morphologic Characteristics in Addition to Stenosis in Predicting the Symptomatic Side in Carotid Artery Disease.
DOI 0.3174/AJNR
L.
Saba,
G.
Mallarini.
Window Settings for the Study of Calcified Carotid Plaques with Multidetector CT Angiography.
AJNR Am J Neuroradiol 30:1445–50 _ Aug 2009.
L.
Saba,
R.
Montisci,
R.
Sanfilippob,
G.
Mallarini,
Multidetector row CT of the brain and carotid artery.
The Royal College of Radiologists....
Personal Information
1.dr.
nandini bahri,
MD
Professor and HOD,
dept of radiology,
m p shah medical college and g g hospital,
jamnagar,
gujarat state,
india-361008.
2.dr.
reeta gupta,
MD
Assistant Professor,
dept of radiology,
m p shah medical college and g g hospital,
jamnagar,
gujarat state,
india-361008.
3.
dr.
pankaj watal,
MBBS
3rd year resident,
dept of radiology,
m p shah medical college and g g hospital,
jamnagar,
gujarat state,
india-361008.
