Purpose
MDCT angiography is an accurate,
non-invasive technique for assessing the presence and extent of peripheral arterial occlusive disease. The sensitivity and specificity of MDCT angiography are 95% and 96%,
respectively [1].
The diagnostic applications ofMDCTangiography have extremely improved considerably because of its high spatial resolution,
the use of fast contrast material injection rates,
novel reconstruction algorithms and postprocessing tools.
However MDCT angiography has some critical disadvantages such as sensitivity to number of artifacts and especially radiation dose that is a persistent problem with modern MDCT....
Methods and Materials
This prospective study was approved by the institutional review board and informed consent was obtained from all patients.
90 consecutive patients with clinically indicated CTA were enrolled in the study and randomized into three groups based on CTA protocols: first (120kV 200mAs),
second (80kV 200mAs) and third (120 kV 50mAs).
Exclusion criteria were renal dysfunction and allergy to iodine.
All had suspected lesions of aorta and peripheral vessels.
Examination protocols
CTA examinations were performed on a 256-MDCT (Brilliance iCT,
Philips Healthcare,
Cleveland,
OH).
First group...
Results
90 patients were enrolled in this study: 78 men and 12 women.
Mean age in first,
second and third group was 63±14,5 61±13,8 and 62±11,2 years,
respectively (p=0,696). Mean body weight was 81,3±12,69,
77,4±12,8 and 79,5±16,14 kg,
respectively (p=0,773).
Mean height - 1,69±0,27m,
1,7±0,3 and 1,70±0,43m,
respectively (p=0,859).
The BMI ranged from 21 to 38 kg/m2 and were not significantly different between groups (p=0,17,
0,614,
0,297,
respectively).
The mean intraarterial attenuation in 1,
2,
3 group was 315±6HU,
448±76HU,
334±33HU,
respectively,
but significantly higher in...
Conclusion
Some reports have investigated the feasibility of MDCT for the assessment of patients with PAOD,
authors reported high degree of accuracy in the evaluation of the site and degree of stenosis,
with results comparable with those of DSA. Some studies revealed that diagnostic quality of images can be achieved with a lower radiation dose.
They showed high sensitivity,
specificity,
accuracy,
PPV and NPV for detecting of significant stenosis using low-dose protocols [2,3].
Our results shows average radiation dose reduction up to 70% achieved using “80kV”...
References
Met R,
Bipat S,
Legemate DA,
Reekers JA,
Koelemay MJ (2009) Diagnostic performance of computed tomography angiography in peripheral arterial disease: a systematic review and metaanalysis.
Jama 301:415–424
Utsunomiya D., Oda S.,Funama Y.,Awai K.,Nakaura T.,Yanaga Y.,Hirai T.,Yamashita Y.
Comparison of standard- and low-tube voltage MDCT angiography in patients with peripheral arterial disease.
European Radiology November 2010,Volume 20,Issue 11,pp 2758-2765
Fraioli F.,Catalano C., Napoli A.,Francone M.,Venditti F.,
Danti M.,Pediconi F.,Passariello R.
Low-dose multidetector-row CT angiography of the infra-renal aorta and lower extremity vessels: image quality and...