Describe imaging findings in hepatic candidiasis (ultrasound,
CT scan and MRI) 2.Determine the evolutionary aspects in MRI 3.
Review of spleen and kidneys candidiasis
Candidosis : Opportunistic infection Hepatic candidosis is a severe form with significant mortality (33%) Incidence : Estimated between 3 to 29% in acute leukemia Increasing recently Population at risk is : acute leukemia prolonged neutropenia (>10 days) broad spectrum antibiotics total parenteral nutrition multisite colonization by candida spp Physiopathology (figure 1) : 2 gateways : vascular or digestive Diagnostic (figure 2) : Very difficult EORTC/MSG Criteria
Findings and procedure details
Ultrasound (figure 3) : Easy access particularly if aplasia in intensive care Hepatomegaly 4 differents patterns : aspecific abcess bull's eye wheel within wheel wagon wheel In chronic lesions,
calcifications may appear CT-scan (figure 4) : Sensibility > Ultrasound 3 differents patterns : hypodense micronodular lesion with peripheral enhancement hypodense without contrast,
non visibleat portal phase double target MRI : Sensibility > CT-scan 3 phases are described : acute (figure 6) : round...
MRI is a major criteria for the diagnosis of hepatic candidosis MRI allows to assess the phase and treatment response MRI allows the diagnosis and monitoring of associated abdominal lesions
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