Learning objectives
Thispictorial review illustrates the radiological manifestations of extra-pulmonary tuberculosis.
This will highlight key features that favour a diagnosis of tuberculosis (TB) over other pathologies and discuss extra-pulmonary TB complications.
Background
The worldwide incidence of TB is rising due to increased migration,
a rising incidence of HIV,
and an increase in multi-drug resistant strains.
The main form of transmission of TB is airborne and thus involves inhalation into lung tissue.
TB has historically been more prevalent in low socio-economic populations and also in overcrowded environments [1].
The incidence of reactivation ishigher in the immunocompromised,
such as those with HIV; reports show this to be an estimate 16-27 times higher risk [1].
The ability of TB to...
Findings and procedure details
TB is most commonly limited to the chest,
but recognition of the radiological findings of extra-pulmonary TB,
which can often mimic other disease entities,
is an important step in accurate diagnosis.
We aim to illustrate the common imaging findings in a system based approach and will cover:
Cardiac
Central nervous system
Head and neck
Musculoskeletal
Gastrointestinal/abdominal
Genitourinary
Cardiac
Rare
Via lymphatic spread
Imaging findings on CT - pericardial effusion with irregular pericardial thickening (See Fig. 1 )
A history of pulmonary TB should raise suspicion...
Conclusion
Extrapulmonary TB can involve any system in the body as outlined and mimics other diseases. Diagnosis requires a high index of suspicion especially in high risk groups to instigate timely treatment and prevent significant complications.
References
[1] GLOBAL TUBERCULOSIS REPORT 2017.
World Health Organisation.
[2] P.
Kumar and M Clark,
Kumar and Clark Clinical Medicine,
5th edition.
2002
[3] Grainger.
Grainger and Allison’s Diagnostic Radiology,
6th edition.
2015
[4] Burrill J,
Williams CJ,
Bain G,
Conder G,
Hine AL,
Misra RR.
Tuberculosis: a radiologic review. Radiographics.
2007 Sep-Oct;27(5):1255-73.
[5] Muttarak M,
Peh WC,
Lojanapiwat B,
Chaiwun B (2001) Tuberculous epididymitis and epididymo-orchitis: sonographic appearances.
AJR Am J Roentgenol 176: 1459-1466.