Learning objectives
To illustrate the classic imaging appearances of different brain pathologies on diffusion weighted images.
Importance of addition of diffusion weighted imaging to routine brain imaging.
Background
Diffusion-weighted imaging (DWI) has become a pillar of current neuroimaging and has revolutionised stroke imaging since its introduction in the mid-1980s.
DWI provides image contrast that is dependent on the molecular motion of water.
Diffusion abnormalities represent alterations in the random movement of water molecules in tissues,
revealing their micro architecture,
and occur in many neurological conditions1.
In a DWI sequence diffusion sensitization gradients are applied on either side of the 180° refocusing pulse.The parameter “b value” decides the diffusion weighting and is expressed in...
Findings and procedure details
PICTORIAL REVIEW OF THE CLINICAL APPLICATIONS OF DWI IN PEDIATRIC IMAGING
The practical applications of DWI are inidentifying regions and patterns of abnormalDWI signal and further characterizing them to low or high ADC’s values.
In this poster wewill demonstrate various disease processes associated with diffusion restriction in pediatric neuroimaging.
CEREBRAL ISCHEMIA
Relatively rare disease,
having an estimated incidence of 2.5–13/100,000/year but remains one of the most common causes of death in childhood.
The pathophysiology of restricted diffusion isCytotoxic edema causing cellular swellingand decreased extracellular space...
Conclusion
Apart from acute ischemia,
DWI plays a key role in understanding various pediatric pathologies.
Familiarity of different DWI appearances can be crucial in facilitating an accurate diagnosis,
provide important information about pathophysiology and prognosis of the diseases and guide adequate therapeuticinterventions
References
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