Learning objectives
The aim of this work is to illustrate imaging findings of primary lung carcinoma metastases in unusual sites.
Background
Primary lung carcinoma is the most common cancer worldwide.
About 50% of patients have metastases at initial presentation.
The most frequent metastatic sites are respiratory system,
brain,
bone,
liver,
and adrenal glands.
Other sites such as spinal cord,
pancreas,
bowel,
peritoneum,
spleen,
orbits are less frequently affected.
They are associated with worst prognosis.
Increased knowledge of metastatic patterns is essential in the treatment of patients.
Findings and procedure details
Uncommon metastases were diagnosed at anatomical sites such as the spinal cord,
kidney,
pancreas,
spleen,
peritoneum,
intestine,
corpus callosum,
orbit.
Spinal cord metastases:
Although spinal cord is not considered as a common metastatic site,
lung and breast cancers appear to be the most frequent source of intramedullary spinal cord metastases.
Cervical,
thoracic and lumbar spine are equally affected.
Symptoms include:motor weakness,
pain and sensory disturbance.
MRI is the imaging modality of choice.
Imaging findings include hyper T2 intramedullary lesions with enhancement.
At diagnosis,
most patients...
Conclusion
Primary lung carcinoma metastases should be considered in both common and uncommon sites.
No specific imaging appearance was demonstrated.
References
Niu FY,
et al.
Distribution and prognosis of uncommon metastases from non-small cell lung cancer.BMC Cancer.2016;16:149.
Palmowski M,
Hacke N,
Satzl S,
Klauss M,
Wente MN,
Neukamm M,
et al.Metastasis to the pancreas: characterization by morphology and contrast enhancement features on CT and MRI.
Pancreatology 2008;8:199–203.
WSSung,MJSung,JHChan,et al.Intramedullary spinal cord metastases: a 20-year institutional experience with a comprehensive literature review
World Neurosurg,2013;79:576-584.
Zhou C,
Urbauer DL,
Fellman BM,
et al.Metastases to the kidney: a comprehensive analysis of 151 patients from a tertiary referral center.Brit J...