Aims and objectives
Coronary Artery Disease is a main cause of mortality around the globe.
According to the World Health Organization (WHO),
cardiovascular disease is a group of conditions that affect the heart and blood vessels.
Approximately 17.5 million people died because of cardiovascular disease in the year 2012,
which represent 30% of the total.
7.4 million of them were caused by coronary disease and 6.7 million were caused by acute stroke,
moreover,
it affects predominantly medium income countries.
Regarding the risk factors,
unhealthy diet habits and physical...
Methods and materials
Calcium Score studies are made at our Institution with a Philips Brilliance 64-slice CT Scanner.
The images were obtained with ECG-gating.
Each slice has a 3mm thickness,
tube voltage of 120 kVs with a radiation dose less than 2 mSv. All studies were interpreted by radiologists and cardiologists with speciality in Cardiovascular imaging.
Clinical and laboratory data necessary for the Framingham risk score calculator and the AHA/ACC ASCVD risk algorithm were obtained from the personal file of each patients with their previous consent.
This data...
Results
By segmenting our sample in male and female patients,
the correlation between Agatston calcium score and ACC/AHA ASCVD algorithm was mild with an R-value of 0.36 (p-value < 0.001) for the female patients,
whereas the male population had an R-value of 0.39 (p-value< 0.001)
The correlation between Agatston calcium score and the Framingham score is mild for both female and male patients with an R-value of 0.37 (p-value<0.00) and 0.35 (p-value <0.00),
respectively.
Body mass index has a mild correlation with the Agatston calcium score...
Conclusion
The correlation between Agatston Calcium Score and clinical cardiovascular assessment methods such as the Framingham risk score and the ACC/ AHA risk algorithm is mild.
It is important to consider the Agatston Calcium Score and the cardiovascular risk scores as complements of each other and not as substitutes.
Anthropometric measures such as body mass index and abdominal circumference have a very low correlation with the Agatston calcium score in female patients,
therefore,
we do not encourage further analysis.
In the case of our male patients...
Personal information
Aldo Javier Vázquez Mézquita,
MD
MSc Imaging Candidate,
The University of Edinburgh
Centro Médico ABC,
Mexico City
Radiology and Molecular Imaging Department
Paseo de Tullerías #130 7,
Naucalpan
Zip Code: 53125.
Estado de México,
Mexico
Phone: +5215533340179
e-mail:
[email protected];
[email protected]
References
1.
Enfermedades cardiovasculares.
Centro de Prensa.
Organización Mundial de la Salud.
2015.
Available from http://www.who.int/mediacare/factsheets/fs317/es/
2.
Posadas-Romero C et al.
Prevalencia y extensión de la calcificación arterial coronaria en población mexicana asintomática cardiovascular: estudio Genética de la Enfermedad Ateroesclerosa.
Arch Cardiol Mex.
3017; 87 (4): 292-301.
3.
Han D,
Lee JH,
Hartaigh B,
Min JK.
Role of computed tomography screening for detection of coronary artery disease.
Clin Imaging [Internet].
2016;40(2):307–10.
Available from: http://dx.doi.org/10.1016/j.clinimag.2015.07.002
4.
Sandfort V,
Bluemke DA.
CT calcium scoring.
History,
current status and...