Learning objectives
Aim of this paper is to show possible ways andtechniquesof pancreas biopsies and their complications.
Background
Solid pancreatic masses are predominantly malignant,
and pancreatic adenocarcinomas are the most common type of tumor in front of endocrine neoplasms of the pancreas.
Diagnosis and management of pancreatic cancer requires a multidisciplinary approach,
and CT is recommended as the first step in assessing the extent of the disease.
Pancreatic ductal adenocarcinoma is resectable in only 15-20% of patients at the time of diagnosis,
and histological evidence is usually required before initiating chemotherapy or entering a clinical trial.
There are several methods for pancreatic biopsy....
Findings and procedure details
Biopsy methods:
CT-guided biopsies
Ultrasound-guided biopsies
Also it can be done by:
Surgical biopsy
Endoscopic ultrasound biopsies
Biopsies during ERCP
Techniques:
Fine-needle aspiration (FNA)
Core-Needle Biopsy (CNB)
Fine-needle aspiration (FNA) is a useful technique for malignancy confirmation,
but requires a pathologist with cytology experts to obtain a reliable diagnosis.
Core-Needle Biopsy (CNB) has the advantage of providing a better tissue sample,
allowing further differentiation of the lesion
Biopsy pathways are divided into three categories:
- trans organic biopsy
- trans-mesenteric path
- posterior retroperitoneal approach...
Conclusion
Biopsies guided by ultrasound and CT are less invasive,
faster,
cheaper,
and exceptionally reliable methods for the diagnosis of pancreatic lesions.
References
1.Ultrasound-Guided Percutaneous Core Needle Biopsy for the Diagnosis of Pancreatic Disease Ying Huang,
Jingwen,
Yun-YunChen and Kao li,
Ultrasound in Medicine & Biology,
2018-06-01,
Volume 44,
Issue 6,
Pages 1145-1154,
Copyright © 2018 World Federation for Ultrasound in Medicine and Biology
2.
Amin Z.,
Theis B.,
Russell R.C.,
et al: Diagnosing pancreatic cancer: the role of percutaneous biopsy and CT.
Clin Radiol 2006; 61: pp.
996-1002