Keywords:
Cardiac, Echocardiography, MR, Comparative studies, Diagnostic procedure, Ischaemia / Infarction
Authors:
E. Chiodi, M. T. Cannizzaro, C. Montalto, B. Malta, Z. Ferrante, M. Natali, M. Bertini, M. Giganti, G. Benea; Ferrara/IT
Methods and Materials
A total of 90 ischemic HF patients were included and divided in 2 groups.
Group 1: 30 patients undergone to LGE-CMR and 2D-speckle tracking echocardiography at baseline.
Scar transmurality was assessed on LGE-CMR images using a 17-segment model.
A transmural scar was defined as having >50% of the thickness in any of these 17 segments.
As a consequence,
a viable segment was defined when scar tissue was < 51% of its thickness.
From 2D-speckle tracking echocardiography was derived global longitudinal strain bulls eye of time to peak longitudinal strain.
Target zone for LV lead placement was defined the most delayed viable segment based on information derived from LGE-CMR and 2D-speckle tracking echocardiography.
Group 2: 60 patients were implanted according current clinical practice with LV lead preferably placed in (postero-)lateral vein without any imaging information.
Response to CRT was defined as reduction of LV end-systolic volume
≥15% at 6 months follow-up.