Purpose
Modifications in diastolic function occur in a broad range of cardiovascular diseases and there is an increasing evidence that abnormalities in left ventricular function may contribute significantly to the symptomatology.
The flow inside the left ventricle duringthe diastole is here investigated by numerical solution of the Navier–Stokes equations under the axisymmetric assumption.
The equation are written in a body-fitted,
movingprolate spheroid,
system of coordinates and solved usinga fractional step method.
The system is forced by a given volume time-law derived from clinical data,
and varying...
Methods and Materials
The study was conducted on 20 patients (figure 5 to 11) whom their LV models were already determined,
based on their echocardiograpic data.
This information along with blood flow parameters including: local interacted force with the myocardial segments,
velocity vectors (local radial,
local longitudinal and local circumferential),
local relative strength of blood with the 16 myocardial segments (radial,
longitudinal and circumferential) and curvature index were defined and used as input into algorithm to solve the partial deferential Navier- Stocks equations.
For all calculations average mean...
Results
In patients with Dilated Cardiomyopathy (DCM),
the vortex was located at the center of the LV throughout diastole and systole and did not redirect flow in a coherent,
sequential fashion as in normal subjects.
In normal subjects,
the average vortex was compact,
elliptically shaped,
and was located apically.
This vortex was persistent during diastole and directs vectors towards the LVOT.
In patients with DCM,
a spherical,
centrally located vortex was observed with incoherent direction of LV flow (Figures 12 to 19)
Conclusion
In the presence of ventricle dilatation the mitral jet extends farther inside the ventricle,
propagation velocity decreases,
and the fluid stagnates longer at the apex.
And blood flow pattern is followed in three distinct branches where two of them are helically back forwarded to the left atrium (mitral regurgitation) and third branch goes to aorta (Figures 20 to 25).
(In compared with the normal fluid dynamic in LV)
For the first time we have innovated a novel software that shows complete blood flow path inside...
References
1- Mersedeh Karvandi,
Saeed Ranjbar,
Seyed Ahmad Hassantash,
Mahnoosh Foroughi.
Brief communication: Mathematical concepts of mechanisms of left ventricular myocardium.
International Journal of Medical Imaging,
2014; 2(2): 19-23.
2- Mersedeh Karvandi,
Saeed Ranjbar,
Seyed Ahmad Hassantash.
Mechanical mitral valve modeling: Advancing the field through emerging science.
International Journal of Medical Imaging,
2014; 2(2): 24-28.
3- Mersedeh Karvandi,
Saeed Ranjbar,
Seyed Ahmad Hassantash .
An essential calculated power formula as a new index to study myocardial function of heart.
International Journal of Clinical Medicine Research,
2014;...