The purpose of using protocol Ca-score for attenuation correction in PET myocardial N13-ammonia in patients with CAD

Congress:

ESCR 2015

Poster Number:

P-0016

Type:

Scientific Poster

Keywords:

Cardiac, Radiation physics, CT, PET-CT, Nuclear medicine conventional, Comparative studies, Computer Applications-General, Statistics, Cardiac Assist Devices, Ischaemia / Infarction, Calcifications / Calculi

Authors:

A. Chernova, I. Aslanidi, I. Shurupova, E. Derevjanko, I. Ekaeva; Moscow/RU

DOI:

DOI-Link:

https://dx.doi.org/

Fig. 1: There were no differences in the two diagrams (left one is protocol with ACCT,...

Fig. 2: We could see the greater reduction of N13 accumulation on basal segments of...

Fig. 3: PET/CT scanner, Biograph, Siemens, 64 slices

Purpose

The purpose of this study is to evaluate the feasibility of using CT protocol Ca-score imnages (CaScCT) for the purpose of attenuation correction (AC) in PET myocardial 13N-ammonia in patients with CAD.

Methods and Materials

The study of 20 patients was performed with rest-stress 13-NH3-PET perfusion imaging with both ACCT and protocol CaScCT for the purpose of AC. The resulting image pair perfusion ACCT and CaScCT divided respectively into two groups, which were compared with each other by value summed rest score (SRS).

Results

The first group included obtained on CaScCT, the second group - standard low-dose CT scan. A strong correlation was found between the SRS in pair groups (r=0.89, p<0,05). Mean value SRS represented as median (25%, 75% range) was in 1 group=0 (0,5.75),the 2 group=1.5 (0,6.0), statistical differences, in 8 patients (40%), the difference was 1-2 points, 3 patients (15%) - 3 points. In 13/20 patients no perfusion defect (DP) was defined, in 6/20 patients DP was determined in both images and in 1/20 revealed only...

Conclusion

1. Advanced protocol PET myocardial CaScCT provides a more complete picture of the destruction by evaluation coronary calcium. 2. CaScCT can be successfully used for AC PET myocardial perfusion imaging alone, it allows to decline the standar ACCT protocol in favor CaScCT, which reduces radiation exposure to the patient.