Keywords:
Tissue characterisation, Contrast agent-intravenous, CT, Contrast agents, Cardiac
Authors:
R. W. van Hamersvelt, M. J. Willemink, A. Schilham, P. A. de Jong, T. Leiner; Utrecht/NL
Purpose
Dual energy CT enables material decomposition imaging (MDI).
MDI can be used for quantitative analysis of contrast agent concentration,
for instance in the context of myocardial perfusion imaging.
Most contrast enhanced DECT studies have been performed with the use of iodinated contrast media,
a safe contrast agent in most patients.
However,
ioindated contrast media is associated with contrast-induced allergic reactions and nephropathy which can cause acute renal dysfunction [1,
2] and significant morbidity and mortality,
especially in high risk patients [3,
4].
In these patients gadolinium based DECT may allow for a quantitative assesment of perfusion defects. The purpose of this study was to evaluate the feasibility and accuracy of gadolinium quantification using a dual-layer spectral detector CT (SDCT) system.