Keywords:
Tissue characterisation, Pathology, Hyperplasia / Hypertrophy, Surgery, Physiological studies, Physics, MR-Functional imaging, MR-Angiography, MR, Vascular, MR physics, Cardiac
Authors:
O. Y. Dariy, E. Glazkova, S. Aleksandrova, V. Makarenko; moscow/RU
Results
Of the 11 HCM patients, all patients had outflow obstruction (Table 1).
Data |
Obstructive (n=8, 6males and 2 females) |
Non-obstructive HCM (n=3, 2 males and 1 female) |
control group (n=4) |
age,years |
48±13 |
40±11 |
43±12 |
septal thickness,mm |
20±0,65 |
17±0,69 |
10±0,1 |
SAM positive (n) |
8 |
0 |
0 |
LVOT, mm |
19.8±2.84 |
22±3.1 |
22.6±3.5 |
Data were obtained on the geometry and dynamics of vortex diastolic flows in the LV of all group patients. HCM demonstrated significantly increase in the distance to the center of the vortex and decrease in the normalized area, decrease peak velocity of the vortex (P < 0.005) compared to controls. The diffuse-septal HCM phenotype was characterized by a minimal vortex peak velocity (Fig 4); the apical one - the maximum vortex sphericity index. For patients with a focal-basal HCM phenotype- the maximum changes in blood flow were determined in late diastole (absence of vortexes).