Keywords:
Tissue characterisation, Pathology, Hyperplasia / Hypertrophy, Surgery, Physiological studies, Physics, MR-Functional imaging, MR-Angiography, MR, Vascular, MR physics, Cardiac
Authors:
O. Y. Dariy, E. Glazkova, S. Aleksandrova, V. Makarenko; moscow/RU
Methods and Materials
We studied 11 patients with cardiac magnetic resonance imaging (CMR) for HCM assessment at Bakulev Scientific Center for Cardiovascular Surgery. Included patients were classified as having obstructive HCM if their echocardiographic- assessed peak resting LVOT pressure gradient was >30 mmHg. All measurements were performed on 1.5-T MR systems (Avanto, Siemens, Germany).
The 3 (28%) patients were with HCM apical phenotype; 4 (36%) with diffuse-septal (Fig.2) and 4 (36%) with focal-basal phenotype.
We also performed 4 cardiac (CMR) of healthy controls (43±12 years).
All patients underwent the standart CMR protocol with an additional phase-contrast sequence of the LV area (4D flow (field strength = 1.5T, resolution = 2.2-4.0 × 2.2-4.0 × 2.5-3.2 mm(3) ; venc = 80-100 cm/s; TE/TR/FA = 3.36msec/79.95msec/15°) for the in vivo assessment of 3D blood flow velocities with full coverage of the LV (Fig 1).
Postprocessing carried out in 4D FLOW (Siemens).