Flow mediated dilation of posterior tibial artery in geriatric population – a pilot study

Congress:

ESCR 2019

Poster Number:

P-0060

Type:

Poster Abstract

Keywords:

Geriatrics, Dilatation, Arteriosclerosis, Diagnostic procedure, Ultrasound, Vascular, Cardiovascular system, Arteries / Aorta

Authors:

M. Kotecki, J. Obiała, A. Skoczylas, I. Sudol-Szopinska, T. Targowski, A. Nowicki, R. Olszewski; Warsaw/PL

DOI:

DOI-Link:

https://dx.doi.org/

Fig. 1: Pictorial overview of FMD assessment on posterior tibial artery

Fig. 2: A - hyperechoic 2,3 mm thick plaque in the bulb of common carotid artery; B -...

Fig. 3: Schematic presentation of undergoing processes during FMD assessment; in this...

Fig. 4: %FMD in a patients without lung disease vs lung disease group; p=0.04

Purpose

Cardiovascular diseases are the leading cause of death in the modernworld, especially among older population. However, there is still a lack ofstratification strategies assessing the cardiovascular risk in geriatricpopulations. Novel noninvasive method which focuses on flowmeditated dilation (FMD) indirectly shows the function of endothelium. The aim of this study was assessment of FMD in left posterior tibialartery and carotid arterial stiffness, intima media thickness (IMT) ofcarotid arteries, carotid and femoral plaques in geriatric population (Fig. 1).

Methods and Materials

Patients were enrolled from the Department of Geriatrics, NationalInstitute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland. Every patient has filled a short questionnaire regarding their basic- and personal data. More sufficient data were obtained after patient hospitalization. The ultrasound examination was performed with the use of Samsung RS-80A with Prestige. Prior to the study all patients have been fasting for at least 6 hours, ceased smoking, alcohol and caffeine consumption for at least 12 hours. The vasodilatory agents were withdrawn on the day of the...

Results

33 patients were recruited for the study (28 woman, mean age 77.3 +/-7.86). Maximal IMT of left carotid artery was higher (1.11 vs 0.91 mm ; p= 0.03) and FMD was lower (9.3 vs 14.1 %; p=0.04; Fig. 4) among patients diagnosed with lung diseases, while no significant correlation with cardiovascular diseases has been found. The presence of plaques in left common femoral artery lead to lower diameter of posterior tibial artery (1.65 vs 2.03 mm; p=0.02). Finally, FMD correlated with left IMT thickness (p=0.01;...

Conclusion

Performed study revealed association between IMT, FMD andpulmonary disorders in geriatric population, while there was no significant correlation with cardiovascular diseases. Moreover, our study revealed utility of FMD measurement on posterior tibial artery. Our cohort will be followed-up, further investigations are necessary tounderstand this phenomenon.

Personal Information

M. Kotecki1, J. Obiała2, A. Skoczylas3, I. Sudoł-Szopińska1, T. Targowski3, A. Nowicki4, R. Olszewski2,4 Department of Radiology, NationalInstitute of Geriatrics, Rheumatology and Rehabilitation Department of Gerontology, Public Health and Didactics, National Institute of Geriatrics, Rheumatology and Rehabilitation Department of Geriatrics, NationalInstitute of Geriatrics, Rheumatology and Rehabilitation Institute of Fundamental Technological Research - Polish Academy of Sciences

References

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