Authors:
L. D'Errico1, G. Aquaro1, A. Pingitore1, E. Strata2, G. Di Bella3, S. Molinaro1, M. Lombardi1, C. Bartolozzi1; 1Pisa/IT, 2Firenze/IT, 3Messina/IT
DOI:
10.1594/ecr2011/C-2073
Results
As shown in Table 1,
126 subjects (31.8%) had RV abnormalities (RVA group).
Of these,
61 subjects (15.4%) were included in RVA-2 and 65 (16.4%) in the RVA-1 group.
The remaining 270 subjects (68.2%) were included in the no-RVA group.
Of the 61 patients in the RVA-2 group,
6 patients had WM abnormalities (akinesia/bulging) as major criteria plus 2 minor criteria (mild-to-moderate RV dilation and frequent PVCs),
allowing a definite diagnosis of ARVC/D by applying the Task Force Criteria,
whereas in the remaining 55,
the presence of signal alterations as only a surrogate major criterion (fat infiltration) plus at least 2 minor criteria did not allow a definite diagnosis.
The occurrence of a cardiac event was significantly higher in the RVA group than in the no-RVA group (hazard ratio [HR]: 32.0; 95% confidence interval [CI]: 4.2 to 244.8; p = 0.001).
Event-free survival curves for these 2 groups are shown in Figure 2.
Both the RVA-2 (HR: 48.6; 95% CI: 6.1 to 384.8; p < 0.001) and the RVA-1 groups (HR: 18.2; 95% CI: 2.0 to 162.6; p = 0.01) had more cardiac events and a worse survival curve than the no-RVA group.
(Fig.
3).