ECR 2013 / B-0557
FDG-avid duodenal lesions: a retrospective analysis of their significance in oncology practice
Keywords:
Small bowel, PET-CT
Authors:
S. Puri, L. Jones, J. Strang; Rochester, NY/US
Purpose
Introduction
- Many colorectal lesions with focal 18F-FDG uptake discovered incidentally on 18F-FDG PET/CT are neoplastic and often malignant,
with a positive predictive value of 87%.
- Several large studies of focal 18F-FDG bowel uptake report a very low incidence of pathologic uptake within the small bowel (SB).
This is not surprising as both benign and malignant small bowel neoplasms (SBN) are relatively uncommon.
Subsequently,
there is paucity of data on the PET/CT findings of SB lesions.
- CT detects approximately 73% of SBN.
The actual incidence of SB tumors detected with 18F-FDG PET/CT is unknown.
- The duodenum is often overlooked on CT and PET/CT scans
- It is the smallest section of the small bowel,
approximately 25-30 cm long.
Its length belies its importance in the gastrointestinal tract.
- Its intraperitoneal and retroperitoneal location and proximity to the gallbladder,
pancreas,
stomach,
spine,
aorta,
liver,
and other segments of the gastrointestinal tract result in duodenal involvement by a multitude of primary and secondary processes.
- Duodenal FDG uptake is seen occasionally,
with a variety of patterns,
on PET/CT exams performed for evaluation and management of a wide spectrum of malignancies.
- The duodenum is often overlooked on CT and PET/CT scans
- It is the smallest section of the small bowel,
approximately 25-30 cm long.
Its length belies its importance in the gastrointestinal tract.
- Its intraperitoneal and retroperitoneal location and proximity to the gallbladder,
pancreas,
stomach,
spine,
aorta,
liver,
and other segments of the gastrointestinal tract result in duodenal involvement by a multitude of primary and secondary processes.
- Duodenal FDG uptake is seen occasionally,
with a variety of patterns,
on PET/CT exams performed for evaluation and management of a wide spectrum of malignancies
Objective
- Determine the significance of various patterns of 18F-FDG uptake within duodenum on PET/CT in an oncologic population.