Keywords:
Cancer, Experimental investigations, MR-Diffusion/Perfusion, MR, Pelvis, Genital / Reproductive system male
Authors:
C. Cecchelli, C. Gaudiano, F. Busato, R. Golfieri; Bologna (BO)/IT
DOI:
10.1594/ecr2013/C-1295
Conclusion
Endorectal-MRI is an important tool in the evaluation of post-prostatectomy bed, due to its high contrast resolution which is able to provide an excellent evaluation of the vesico-urethral anastomosis.
T2-weighted imaging alone showed an inferior diagnostic performance in detecting areas/nodules of local recurrence compared to DWI and DCE-MRI.
We demonstrated that DCE-MRI,
combined with DWI,
showed a better diagnostic performance in detecting areas of local recurrence compared to the two techniques evaluated separately.
In addition,
we suppose that a characterization of soft tissue in RP bed could be possible by using DCE-MRI; in fact we found a prevalence of type 3 T/I curves (72.%) in patients without local recurrence,
while in positive patients type 1 (27%) and type 2 (64%) T/I curves were prevalent.
These results suggest that on the one hand type 3 curves could correspond to fibrotic tissue and on the other hand type 1 or type 2 T/I curves could be expression of a local recurrence.
Further studies with larger patients population are necessary to confirm these important observations.