Keywords:
Multidisciplinary cancer care, Lymphoma, Haematologic diseases, Staging, Imaging sequences, Comparative studies, PET-CT, MR-Diffusion/Perfusion, MR, Oncology, Lymph nodes, Haematologic
Authors:
M. Ficco1, N. Maggialetti2, C. Ferrari3, C. Minoia1, F. IUELE3, C. Buquicchio4, A. Guarini1, C. M. Florio1, G. Rubini3; 1Bari/IT, 2Molfetta/IT, 3Bari (BA)/IT, 4Trani/IT
DOI:
10.1594/ecr2013/C-1937
Methods and Materials
We enrolled twenty-five consecutive patients with new diagnosed lymphoma histologically confirmed (see the table for the sample’s features).
All of them underwent whole-body MRI (coronal T1-weighted,
coronal STIR and axial DWIBS sequences) and performed 18F-FDG-PET/CT,
within 2 weeks before/later whole-body MRI.
Axial DWIBS sequences included three acquisitions of b factor (0,
500 ,
1000).
The total acquisition time for Whole Body-MRI/DWIBS was approximately 25 minutes.
Whole Body-MRI/DWIBS was independently evaluated by two blinded observers and lymph nodes larger than 10 mm in short-axis diameter,
in the coronal plane on T1-weighted and STIR images, were considered positive.
The agreement between WB-MRI/DWIBS and 18F-FDG-PET/CT for each of the nodal localizations (schematically summarized in: neck-axilla-mediastinum-abdomen-pelvis and femoral stations) and extranodal ones of lymphoma was evaluated.
The overall agreement between the two technique in lymphoma staging,
according to Ann Arbor criteria,
was also evaluated.