Keywords:
Obstruction / Occlusion, Imaging sequences, MR-Diffusion/Perfusion, MR, Kidney, Abdomen
Authors:
O. T. Kalayci1, M. Apaydin2, F. Sonmezgoz3, S. Calık4, M. Koruyucu1; 1İzmir/TR, 2IZMIR/TR, 3Malatya/TR, 4Elazıg/TR
DOI:
10.1594/ecr2013/C-1990
Purpose
Diffusion weighted-magnetic resonance imaging (DW-MRI) is used to show Brownian motion of the spins in biologic tissues,
can be use to differentiate normal and abnormal structures of tissues.
The apparent diffusion coefficient (ADC),
as main quantitive parameter used to interpret DW-MRIs,
combines the effects of capillary perfusion and water diffusion in the extracellular extravascular space [1].
DW imaging has been extensively used in neuroradiology.
The applications of DWI in abdominal disease have lagged behind neurologic applications.
Because DW-MRI of abdominal organs is much more difficult to perform as a result of physiologic motion artifacts and heterogeneous composition of the organs [2].
With the advent of echoplanar imaging (EPI) in conjunction with breath-holding,
DWI of the abdomen has become possible with fast imaging times minimizing the effect of gross physiologic motion from respiration and cardiac movement.
The kidney is an interesting organ in which to measure ADC values,
because of its high blood flow and water transport functions.
With its complex anatomic structure and physiology,
kidney is extremely challenging for DW-MRI.
[3,
4].
Obstructive uropathy is a structural or functional hindrance of normal urine flow that causing hydronephrosis.
It can occur due to some benign and malign conditions.
To date,
no papers have been published on MR diffusion imaging in patients of obstructive uropathy for discrimination benign and malignant etiology.
The purpose of this study was to evaluate the capability and reliability of DW- MRI in differentiation between benign and malignant causes in obstructive uropathy.