This poster is published under an
open license. Please read the
disclaimer for further details.
Keywords:
Outcomes, Multidisciplinary cancer care, Cancer, Treatment effects, Efficacy studies, Ablation procedures, Ultrasound, Percutaneous, CT, Management, Interventional non-vascular, Abdomen
Authors:
S. W. Jeon, J. H. Kwon, M. J. Kim; Daegu/KR
DOI:
10.1594/ecr2014/C-0745
Aims and objectives
Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third most frequent cause of cancer death(1,2).
Although tumor resection remains a first-line treatment,
only approximately 30% of patients can benefit from curative therapies such as resection or liver transplantation and approximately 70% of patients are not candidates as a result of poor hepatic reserve or tumor burden(3).
So nowadays locoregional treatments such as radiofrequency ablation (RFA),
percutaneous ethanol injection (PEI) and transcatheter arterial chemoembolization (TACE) are widely performed to unresectable HCC because of minimal invasiveness and preservation of liver function(4).
Among these locoreginoal treatments,
RFA has steadily become first-line ablative management of small HCC(<3cm) because of higher rates of complete tumor necrosis with fewer numbers of treatment sessions(5).
But RFA has limitations and risks to ablate HCCs abutting on large blood vessels and located closely to liver capsule or vital organs,
on account of relatively higher complication rate and local recurrence rate.
So that means RFA high-risk group(6).
In these high risky located HCCs which are difficult to ablate with RFA alone,
combined use of RFA and PEI could produce synergistic tumoricidal effect and complementary role each other.
The purpose of this study was to evaluate effectiveness,
safety and follow up results of combined use of RFA and PEI of HCCs difficult to ablate with RFA alone.