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Keywords:
Abdomen, Oncology, Paediatric, Ultrasound, Ultrasound-Colour Doppler, Ultrasound-Power Doppler, Diagnostic procedure, Staging, Screening, Cancer, Congenital, Pathology
Authors:
I. Begun, O. Krasko; Minsk/BY
DOI:
10.1594/ecr2014/C-1997
Results
There were a correlation between tumor volume and infants ages (r = 0.52; p<0.05). Nonlinear model using the Gompertz function describing the growth of the tumor was fitted using logarithmic form of equation (1) (Fig.
9)
Fig. 9: Nonlinear model using the Gompertz function describing the growth of the tumor was fitted using logarithm form of equation (1)
: for time point t0 = 0 (day of birth),
and time point (prenatal diagnosis) t0 = –48 days (see Table1 in Fig.
10,
Fig.
11).
Fig. 10: Table 1
We obtained significant estimation of the tumor volume at time point of birth,
but non significant estimation at the 32-33th weeks of pregnancy.
Estimation the timepoint of maximum rate according equation (3) was tmax = 124 days from birth.
According to the fitting results was revealed that at the time of prenatal diagnosis malignant tumor in the fetus they are can not reach to macrolevel volume threshold to start them visualizing at the 32-33th week of pregnancy.
With the other hand based on the evaluation of the parameters model Gompertz was calculated the point of maximum postnatal rate of tumor growth - tmax = 124 day from birth.
We evaluated the result tmax= 124 from the viewpoint of the general indicator of clinical characteristics - of clinical stage of disease.
It was found that the number of patients with favorable vs unfavorable stages of disease statistically significantly different (see Table 2 in Fig.
12).
Fig. 12: Table 2