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Keywords:
Dementia, Diagnostic procedure, CT, Neuroradiology brain
Authors:
D. Van Westen1, G. Torisson2, E. Londos2, L. Stavenow2, L. Minthon2; 1Lund/SE, 2Malmö/SE
DOI:
10.1594/ecr2014/C-2077
Aims and objectives
Medial temporal lobe atrophy (MTA),
a morphological hallmark of Alzheimers disease (AD),
is also encountered in normal aging,
cerebrovascular disease and neurodegenerative disorders other than AD [1].
MTA is easily and reliably assessed from computed tomography (CT) using a visual rating scale that has shown very good agreement with manual volumetry and is related to memory function in AD [2,
3].
However,
when imaging is performed outside the workup of dementia,
MTA may be underreported for example when cognitive decline may not yet have been recognized,
or when imaging is performed in the acute setting with the aim to rule out obvious pathology such as stroke or hemorrhage.
We have previously demonstrated that cognitive decline is frequent and frequently unrecognized in medical inpatients [4].
Here we reassess cranial computed tomography (CT)s from these patients for MTA,
compare results with cognitive tests and determine the importance of MTA for survival.