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Keywords:
Colon, Abdomen, Oncology, CT, Diagnostic procedure, Neoplasia
Authors:
E. Rosado, A. S. C. C. Germano, A. M. D. Costa, R. Theias, A. P. Gomes, C. Leichsenring, I. Santiago; Amadora/PT
DOI:
10.1594/ecr2015/B-0735
Conclusion
Our study suggests that:
- Optimized MDCT is a specific,
accurate and reproducible method for distinction between LACC and NLACC.
- There is a minimal risk of overtreatment of low-risk patient
Other studies have also shown a good accuracy of MDCT in CC staging:
1.
A metha-analysis [5] published on this topic concluded that preoperative CT can be used to accurately distinguish between tumours confined to the bowel wall and those invading beyond the muscularis layer (differentiation between T1-T2 versus T3-T4):
2.
Nørgaard A et al.
also evaluated MDCT performance in the differentiation between LACC and NLACC:
- T staging accuracy: 69%
- 7% overstaged / 24% understaged
- Identification of LACC was 73% accurate compared with histology (S=70%; E=78%; PPV=81%; NPV=66%)
Study
|
Accuracy
|
S
|
E
|
PPV
|
NPV
|
Rosado E
|
75-88%
|
64%-82%
|
84%-92%
|
50%-70%
|
88%-97%
|
Nørgaard A
|
73%
|
70%
|
78%
|
81%
|
66%
|
Comparison between Nørgaard A.
study and ours reveal a very similar overall accuracy for MDCT.
Both studies emphasise that:
- Optimized MDCT seems to be an accurate method for selection of colon cancer patients who may benefit from NACT.