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Keywords:
Tissue characterisation, Cancer, Ablation procedures, Ultrasound-Colour Doppler, Ultrasound, Elastography, Thyroid / Parathyroids, Contrast agents
Authors:
H. Wu1, Q. Chen2, Y. Liu3, J. Luo2, J. Chen2, Q. Zhou2; 1Zunyi/CN, 2Chengdu/CN, 3Beijing/CN
DOI:
10.1594/ecr2015/C-1975
Results
29 benign nodules and 14 malignant nodules were in category 3 and 15 benign nodules and 31 malignant nodules were in category 4.The maximum diameter of the nodules was 2.30-28.50mm(9.09±5.01mm for average).The results of Logistic regression analysis for CEUS showed:the most effective variable were post-enhancement region,enhancement time and peak intensity(P<0.05).The sensitivity,specificity,accuracy,PPV,NPV and area under the curve(AUC)of it were 82.2%,
72.7% ,77.5%,
82.2%,
72.7% and 0.850(95%CI=0.770-0.930) respectively.According to the SWE results,
the sensitivity,specificity,accuracy,PPV,NPV and AUC were 66.7%,
93.2%,
79.8%,
90.9%,
73.2% and 0.863(95%CI=0.788-0.937) respectively taking MAXd=28.18kPa(which had the biggest area under those ROC curves) as the cut-off value to distinguish the thyroid nodules.At last,the results of Logistic regression analysis for CEUS and SWE showed:the most effective variable were post-enhancement region,
whether it was centripetal enhancement and whether MAXd surpassed the cut-off value(P<0.05).
The sensitivity,specificity,accuracy,PPV,NPV and AUC of it were 91.1%,
88.6%,
89.9%,
91.1%,
88.6% and 0.935(95%CI=0.883-0.987).