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Keywords:
Ischaemia / Infarction, Imaging sequences, MR-Functional imaging, Cardiac
Authors:
A. Celik1, D. Ahmad2, M. Alfaris2, E. Anazi2, G. Slavin3, P. Ghedin4, A.-M. Mouaz2, A. Brau5; 1Antalya/TR, 2Riyadh/SA, 3Bethesda/US, 4milwaukee/US, 5Munich/DE
DOI:
10.1594/ecr2016/C-0450
Methods and materials
SMART1Map was implemented on a 1.5T MR 450 scanner (GE Healthcare,
Waukesha,
WI) and a 32 channel cardiac coil was used in all exams.
15 patients with suspected coronary artery disease were imaged using SMART1Map sequence prior to contrast injection and myocardial delayed enhancement (MDE) scans.
SMART1Map acquisition collected 5 different slices with 5 saturation delay times TS in 9 heart beats at 1,1,1,2 and 4 heartbeats after saturation.
An additional image,
corresponding to an infinite delay time (TS=∞) was acquired without saturation.
The imaging parameters were TR/TE 2.8/1.2 ms, 45° flip angle,
FOV 38x30cm,
slice thickness/spacing 8.0/5.0mm,
acquisition matrix 160x128,
BW 125kHz,
breath-hold acquisition.
The patients heart rate ranged from 60 to 84 bpm.
Myocardial perfusion MDE and phase-sensitive MDE (PS-MDE) acqusitions were also performed as part of routine cardiac scanning protocol.
For each patient,
multiple ROIs on remote and infarcted myocardium regions were drawn on the left ventricle on the automatically reconstructed T1 maps.
The ROI locations on myocardium were selected using the post-contrast MDE and/or PS-MDE maps as guidance.
The blood T1 values were measured from the left ventricular blood pool from multiple slices placing a single ROI in the blood pool.