Keywords:
Gastrointestinal tract, Oncology, MR, MR-Diffusion/Perfusion, Outcomes analysis, Diagnostic procedure, Cancer
Authors:
L. Yang, B. Wu; Chengdu/CN
DOI:
10.1594/ecr2018/C-0510
Conclusion
The purpose of this study was to identify whether the mrTRG assessed by T2-weighted and diffusion weighted imagies was well corresponding to pTRG,
and to explore its ability in selecting good and complete response after NCRT in LARC.
In our study,
it was found that mrTRG was moderate correspondence with pTRG in general,
but the consistency increased when patients were divided into pCR,
non-pCR and GR,
PR groups.
Our results were similar to Lee et al [8],
who employed a modified 3-point mrTRG.
But Sclafani et al [9] found a low agreement between mrTRG and pTRG,
which might due to their more subdivided 5-point mrTRG definition.
Besides,
mrTRG showed a good capacity in assessing pCR and GR.
In conclusion,
our limited population study indicates that mrTRG can be used as a surrogate for evaluating tumor state before surgery,
which may be helpful to make individualized clinical treatment strategies.
These results need to be further validated in large multi-center prospective studies.