Keywords:
Breast, Mammography, Ultrasound, Vacuum assisted biopsy
Authors:
A. SPEZZACATENE, M. TONUTTI, F. GIUDICI, M. BORTUL, F. Zanconati, M. A. Cova; Trieste/IT
DOI:
10.1594/ecr2018/C-1861
Results
From 2006 to 2016,
among 10200 breast lesions examined with a cytological and micro-histological approach,
we identified 197 B3 lesions (1.9%) in 196 women (age 56±13 years) (Fig.
1).
Papillary lesions represented the predominant histologic subtype (29.4%) (Fig.
2).
112 B3 lesions (57%) underwent excisional biopsy,
with an upgrade rate of 19% and a PPV of 11%,
while 85 B3 lesions (43%) were sent to follow-up.
The B3 lesions investigated with the first cytological approach (63%) were more frequently submitted to surgical biopsy than the B3 lesions investigated with micro-histological examination alone (68% vs 36.1%,
p<0.001) (Fig.
3). Invasive carcinomas were found predominantly in B3 lesions with a microhistological diagnosis of LIN 1-2,
which is associated with the highest rate of malignancy (PPV = 32%) compared to the other histologic subtypes (p = 0.01) (Fig.
4; Table 1).
On the contrary,
no specific mammographic abnormality significantly correlated with the risk of breast cancer (p = 0.11) (Table 2).