Liposarcoma is malign mesenchymal tumor,
which may arise in any region of the body.
Liposarcoma is the most common primary malign neoplasm of the retroperitoneum,
but mesentery and peritoneum are rare locations.
On pathology liposarcomas are classified as well-differentiated,
dedifferentiated,
myxoid,
pleomorphic,
and round cell/cellular myxoid subtypes (2).
Well-differentiated group subdivided into four types; lipomatous,
sclerotic,
inflammatory,
and dedifferentiated liposarcoma.
Prognosis of the liposarcomas varies on the basis of the histological subtype (3,
4).
Liposarcomas can metastasize to different areas of the body but have rarely been demonstrated to metastasize to the liver (< 0.5%) (5).
The most common site of spread is to the lung from liposarcomas and the incidence is dependent on tumor grade and size.
Hepatic metastases from primary soft tissue sarcomas frequently occur in cases of visceral and retroperitoneal liposarcomas.
It is uncommon for extremity liposarcomas to spread to the liver.
It is even rarer for the tumor metastasis to be isolated to the liver (6).
Due to the unusual occurrence of metastatic liposarcoma to the liver,
the specific imaging findings is not well known.
On CT and MR imaging,
well-differentiated subtype is characteristically having similar attenuation or signal intensity equal to those of subcutaneous fat tissue with thickened,
irregular septa,
and minor nodular components (7,
8).
The sclerosing subtype,
a non-fatty liposarcoma,
showed CT attenuation and MR signal intensity that approximated the muscles.
Round cell and pleomorphic liposarcomas,
that have less fatty component,
are high grade malignancies with bad prognoses and high metastases rates to the liver,
lung and brain.
Myxoid liposarcomas,
that have less fatty component,
are intermediate neoplasm that frequently has local recurrence (8).
The CT and MR imaging findings of liposarcomas are closely relative to the histologic subtype.
To our knowledge,
there is not enough study on the imaging features of liver metastases of liposarcomas.
The CT and MRI characteristics of liver metastases may be helpful a few articles about the correlation between the CT and MR imaging findings and histologic subtype of the liposarcomas.
Each histological subtypes of liposarcomas showed different CT and MR images features.
These features seem to be helpful to predict the diagnosis of different histologic subtypes of the liposarcomas.
In conclusion,
liposarcomas may rarely metastases to the liver.
Imaging findings of these metastases should be studied.