Keywords:
Diagnostic procedure, MR, Liver, Metabolic disorders
Authors:
A. Ugarte1, J. M. Alústiza1, E. salvador2, J. I. Emparanza1, J. Sanchez3; 1San Sebastian/ES, 2San Sebastián/ES, 3Madrid/ES
DOI:
10.1594/ecr2018/C-2881
Methods and materials
The research project was approved by the Institutional Research Board and all participant signed informed consent.
Seventy-two patients with different degrees of iron overload were enrolled in the study.
All acquisitions were acquired in a 1.5T Ingenia system (Philips Heathtech,
Best,
The Netherlands).
The magnetic resonance protocol included mDIXON Quant acquisition with six echos (TR/Initial TE/∆TE/flip angle = 6.5ms\1.16ms\0.8ms\5o) and it was used to obtain water,
fat,
fat fraction and T2* maps.
R2* values were obtained in 3 regions of interest (ROIs) placed in right liver lobe avoiding big vessels. Final reported values were obtained as the average of the three different regions.
The R2* values obtained from mDIXON Quant sequence were compared with the estimated iron overload obtained from the FDA-approved MRI method.